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GROWTH FACTOR, GDNF
Descriptors Found:
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DeCS
Descriptor
English
:
Glial Cell Line-Derived Neurotrophic Factor
Descriptor
Spanish
:
factor neurotrófico derivado de células gliales
Descriptor
Portuguese
:
Fator Neurotrófico Derivado de Linhagem de Célula Glial
Synonyms
English
:
GDNF
GDNF Growth Factor
Glial Cell Line Derived Neurotrophic Factor
Glial Cell-Line Derived Neurotrophic Factor
Growth Factor, GDNF
Tree Number:
D12.644.276.860.381.500
D12.776.467.860.381.500
D12.776.631.600.381.500
D23.529.850.381.500
Definition
English
:
The founding member of the
glial cell line-derived neurotrophic factor
family
. It was originally characterized as a
NERVE GROWTH FACTOR
promoting the
survival
of MIDBRAIN
dopaminergic NEURONS
, and it has been studied as a potential treatment for
PARKINSON DISEASE.
Indexing Annotation
English
:
GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTORS
is also available
History Note
English
:
2006(1993)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
51102
Unique Identifier:
D051100
Occurrence in VHL
:
Similar:
DeCS